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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd10300f30fe48525e48b5493139f6907cc389726f5de0d8559cbbf61a0f2d174' 
  AND token = 'IWpe/zei0xOv07A0oSNxQrrSlcE5tYCHuXbI6rfSKPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}