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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '26a2262c4496199d638571526e6cf16112c58d898bfe3039311f463ac9e69c4d' 
  AND token = 'z8P5KGrHIkp82QREvsBfvAtKDaR7FK0lY7tHNTf7Hxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}