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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fe9eef2be7eec8f2527749b40eb770b874b119f51a5e6e7a2161de8485d02166' 
  AND token = 'C8xT7TbSChEZ6fR2NUkzLIj4PlPxFUzXzyOZL7+xqJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}