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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c7d70d2a5b76f08debab47e0ed89cef522690414bb2fbedfe5759f5cb0962748' 
  AND token = 'nITHWfEG5Px34FVLBNYlLdD/zaxCJ4eiQlkPA6va8G4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}