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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '493428db517e9523dd5b5fc5eefbcf9424cd476692f6f94baba6c6233b81cc0f' 
  AND token = 'W8kXDXFZfzCGF3ED/W9PoeBHiBxMP6xuiXLqdC3fN+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}