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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3d59276c3b23bc99a3faaeafde585806ea09273d80f1ef6375feb87af718ed05' 
  AND token = 'datx/9Tf6ImxcfND83D3qMyWcuYpruhfPJ3VNgAM78c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}