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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '46637f70ba872c6cdbb4957c15372e8fa3a73dd03816153962bf11c04f07a407' 
  AND token = 'biQBotpZK1djOUM+SeDu5C4hQ04ZXOPgkcsN/Eebncc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}