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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22c9957847adbb9a744dbee90ab05d38a70a0473446033ef75e8cc3f841ec617' 
  AND token = 'd9u4N1KH+9IXfbCa3r/hs/kz4UdDYpbQpE3YfOf0t4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}