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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '17ea254cff79a3e7c7044ae907baf7e6498b7b2320ffcd66ac7385e00307fd25' 
  AND token = 'RbWXHcg9uFITIKYaI1GZAFrAhAGWxLOAb6QSpDfnwU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}