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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9c111a13fa35218b08ecab8f52f163cc8154f1c41f8b63e1921db6e9b33d0517' 
  AND token = 'V7uopgwYTRyllZ+3ygL4dLE8qqOVJpVpRlRBO3CDPN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}