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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0758f0f9d9de088fa92cd8408adb4ad7bf875f1243d66ccb857cc6bc62b5d886' 
  AND token = 'IHixnz8mDH0+w4gvsC1n+HsFMP1fNtS75bsEP+/XeQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}