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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '27d9367a09be42b8aefa013e8ffdc563b36d89fc64de31f1be17c0801eab28e9' 
  AND token = 'Si+5rTgQ9FbWL6+/DB/rzxsFKej2DENVKOLr/U7NjsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}