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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c387e4fcf587024297671adf982f8cf881b568effbf5af82a61279159cafa783' 
  AND token = '1/Gp1V25vzwe6J9jUypmeB4O29Vn9WwUTatR+poMJSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}