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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e42c8143306acda701c2ee4eff8a0d0d32bbcd7da7126c6ac2b18dfa012291d1' 
  AND token = 'wOXHh/bglVTOx2YqH8EhxkPbXiqFJ2RZfMYJG1G2ppU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}