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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c45af7bcff7be636de3692f114708db7bd949bec0e18b26ed7dbb12bd1bace20' 
  AND token = 'P1jbX3HL7bS5rj6KFVnYgcSE05v3EhLohj1rX4d2Zuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}