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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6a8c9d56d154705d6904aeb5c0861b4420fb7764137d613cf2b40c357bbe2221' 
  AND token = 'gjHgZ1VUHxMdmtYfba6g7TkW7tAYS2hfEaMokfLebDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}