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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2a9f0db4495620e9b5b43651833ad423903a3c12f3cd4b7d8bbfe3215e6690bf' 
  AND token = '//z/pnpNpSh6dg3r9jlCevsukUsAkO1XSLM0+RSOON4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}