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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '43a334d919602e001119d8f914691d7cd5529d57486d657f5d74e6064ced94bc' 
  AND token = 'kESyD+wWESSZUxMxzXm/mUhjA7vb2tzt3ykAKSXDLLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}