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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6300404d946b4d4b6bd27339c9f53652c4c07feec7e8767f47a6cd6971befa9b' 
  AND token = 'TQ7B97Ju6WBSAYTgyTdcPkZNIiDdRlEpkkdyFnerobk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}