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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0a99dce440af548d18449af9d6d8c9f2b69058621d45d6dea6a30a6f3b46d4b8' 
  AND token = 'JiQDa65sVysmZF1LWntokoOiqNxrMn+SSwITHRDyXkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}