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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4943336d2e64c843d185713a8144e2141eb5ca2eebcfd7253becf339d043839b' 
  AND token = 'T588jho3oTU34etBHAPosy0324WAd4b/8v/oDVW1AQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}