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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8c86fb99071044b578a20f01c2bd9d064227659b7a5a9fbcf36cec4a3a860c2c' 
  AND token = 'lTmVO0Mx/mdsjcQ6FlobHKqn3EyNLwxC7R4qa25dny0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}