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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'db5e290b67b4bc91a77711a943e2cce96a9fd30e4e57177d39a537970d46c4d6' 
  AND token = 'U2GiTkkx4PJ8SWpECCrIGbQYpDdEURcW7Y4+iacyqD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}