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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2e09633e980094af65339a29e0ef648b4662a135e83d41127a5c354d62c80d63' 
  AND token = 'Vcq0xIXw6WHrS9MMkTJgR8ZDjusj90rEIq/3sDxarPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}