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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '05030f724ffc18a6159575e3119fd575aaada42ac033747d1057f035cc1f3216' 
  AND token = 'w/Ohi2fCHSCINUyvmgdYIPgoHxTFc6gnjhaN6RGN//Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}