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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4dbca0e37cdba7189a093d3db406c3b1f0c9328528aa927c6ab274ca0987d498' 
  AND token = 'PxQoV5u8ekjZl1MeBWKQBVcuRrp8e3mt6mjNrrBswp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}