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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'aa321ec08851203901979e1d7487997e91e6aba05c9ca31f599924fab61d0aaf' 
  AND token = '6rXiN+PXzP10rNdgu2LSPbCRXBzQ4CQcJSjJqaP1bKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}