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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cfa2e0d025c85d702f1187db738346a9f644edeb593a198fbd820725da1f36c8' 
  AND token = '6Q6gT0k4z4aKycolDIVVdW9AEcpR6R5Tls01XAKUDug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}