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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8272583f7e15d73e39ebe75d74939c70d1c757498e8158c236764a8a37294a24' 
  AND token = 'pw2NrYT2ACusD5CVz6ug2OnCiB1F8dDELTb4BUWD6XM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}