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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '427c8829d36f0e57b651de06c3a7392c44bd4893665e3095474486cea104a13a' 
  AND token = 'NHTxjprVAXrqfAYfvAm6TebO2mf11eLM2+k3Tta79LU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}