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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '95ef79dbef48e7d2a5128e442dc4278d5a2fc409e9c91a4074310dc83263eee8' 
  AND token = 'WE1IAdX2At+QJEwx71nOusy0chXsPuIGT5zlYY2pPw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}