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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9d69a87e06f8c0cc79fbafd65de36fe9fac2ea862dcc7621a1c149d652f8b440' 
  AND token = 'kSPEr88EEM9+OHt/c+HhRP5a/py5jrAVEH6oH4lYzX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}