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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '01f6b512c397f66788daa4f4eba2914b2578b6eb92bebadb06887eafc1f9cbc3' 
  AND token = 'PJ577oDlyV/pA7BBtNvAeHmAVdaFsEd4x7fMZ19zgjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}