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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4271e966b1cd2fbc952820e72f6c2fb7e5cf06065c909b4ee0a7b15aeec3925f' 
  AND token = '6zDfOTaOFzt5Wksh4XVmZYkUtq4+aQqbd9wD149xNyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}