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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9b300c86ce6295ba1dbcfa54de4ac55518fb0e1389cbdac49b8b01dc88046f44' 
  AND token = 'U6LFOj/CBmOJk07wR4dxU8CeGNV6D+Xdj+UERjl8AXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}