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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '59ca2cfb6b1b23f55f9375e9d209831920754dd4519199cef0f5f8158c3e3436' 
  AND token = '0bf0EEUA/3g9Fx0z8yxmfXQyXDlwxFdOgo0rE4MCGjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}