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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'daac2be0f236479e8ca41364f2830f58dc95c9ddaf4bf04a203139bb04d18686' 
  AND token = 'Ob+1Crlx6S10oMzV+rWWBxF4S7Ru1L9Rq2eWUtFNcK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}