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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '709fb5714093e3c8464aaf1a1ed40e617df58d501eb97f17fae7da49a75ed4f4' 
  AND token = 'kcAYqUp7T/V4ZTH0XrSUe8E4aGEXpK8DPzLbP1nqHZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}