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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4ce20ad04cae90146a3332e963cdf101b1378e7b38d677d7fd22f1740328728f' 
  AND token = 'sIYicxN8FLqkFaxyJMilri6w/ULZO92/n5BF7tZo1lU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}