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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a80e822621e0818aeed7c9f7d300b9bd49845be0d7de88220735a8540c5e16f5' 
  AND token = 'tf3hH1gsS8lf6twMGnWEyvoujsmoNRLdRkjLGf5DT1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}