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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49580e8052906b410e17355d7d039ed52f1013026b72f5d9023c84a6b3092736' 
  AND token = 'bjJM6EEMTaP3xoQdrzGrKophWad0pDq/lqdPE1x6efs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}