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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '40bc852d12455c6276e3600a12f6aeb1542b7fec6e3f98dedca0eeec028d620f' 
  AND token = 'JdV0/chcgK/QJpErqbVxMQHOotxvhTqo9oXhJclnRv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}