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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c4133cc4e5df1a8119ed691ceaa1fb929b342d8fb3f5cd395c487984c5e36210' 
  AND token = '9S4DS7YDhQUkTWACeT1967WZ8E1+bOj1JMfFnl/Qm7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}