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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c6d1150819a3fe060e85475bc10c84ebf5fae8005ae58b19833c7000fda4408f' 
  AND token = '4Y3Kb47EdlDmMYqsmcfSrpp1ywAfv8Ynkj63ARgLfDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}