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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9e5705fb68435a6dfa6a2510139f5af0dae8073e0bf4a1b1086f740d2966cead' 
  AND token = 'vO6zEA3n2r7/P2305FsSiZBAmBR2f/nov/4emDbbyjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}