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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2296bd42aff5b4d4b3f0df75ad21acbb016f39e9ad44370071baaa2fbb0d72da' 
  AND token = 'XPLQNJsHLA57p4weRLvQgV9XQh9Rqq9ZUzh4fWPEDGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}