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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '10ca16b1ac6ab6333822762a9952b909b7c0a35aad05873e637df48c324b1cc2' 
  AND token = 'WaI0wp322apIKB6u2snMmdyJjeVOsUX53UDTvtIhiNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}