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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '76aa02307be551d90a5e98533f07583b39095f4424c167d74be5e371e8c14feb' 
  AND token = 'd9V/9sgbGA0IB1KyYI3pE0pMXcVnMMDtYXqidlM/mdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}