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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5fd0246bdbcdb33961a18d2e1e03610ad36cbc2100d316108434d8b8dd0a94da' 
  AND token = 'DPDCbfs8ZeWm8C3L/U3vnsP9NgeCq/ZF7TyaV34p2Kg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}