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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'aa65ce7537f36eba2e78427c54221e760d68f2ed17aef03724a23eee33e9d611' 
  AND token = 'tegiDEqZ+kHOgqa/C0n9TO9ZHa8xQzvmnZmFWT5GZ8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}